Vol.-13, No.-2

ral hepatitis is a major public health problem\\r\\nworldwide. About 8-10%(450-600 million people) of\\r\\nthe world population is infected with either Hepatitis-\\r\\nB (HBV) or Hepatitis-C (HCV) virus both of which can\\r\\nlead to chronic hepatitis, cirrhosis, hepatocellular\\r\\ncarcinoma even death.1,2,3 Hepatitis-A (HAV) and\\r\\nHepatitis-E (HEV) virus infection are also significant\\r\\ncauses of morbidity and mortality in some areas of\\r\\nthe world. Only a few limited information is available\\r\\non the viral interaction or co-infection or superinfection\\r\\namong the HBV, HDV, HCV, HEV and HAV.\\r\\nHepatitis-B infection is endemic in Africa and Asia;\\r\\ntransmitted vertically from mother to newborn or\\r\\nhorizontally between close contacts in the early\\r\\nchildhood.4,5,6 Patients with chronic hepatitis-B are\\r\\nat higher risk of progressive liver disease.7\\r\\n