Vol 17, No.-2 July 2006

Nonsteroidal anti-inflammatory drugs (NSAIDs) are\\r\\ncommonly used to treat pain and inflammation1.\\r\\nAcetyl salicylic acid (Aspirin) is the first non-steroidal\\r\\nanti-inflammatory drug (NSAJD)2,3. NSAIDs\\r\\nconstitute one of the most widely used classes of\\r\\ndrugs, with more than 70 million prescriptions and\\r\\nmore than 30 billion over the counter tablets sold\\r\\nannually on the United States4. Although NSAIDs\\r\\nare generally well tolerated, adverse gastrointestinal\\r\\nevents occur in a small but important percentage of\\r\\npatients resulting in substantial morbidity and\\r\\nmortality.\\r\\n